Products & Applications
Sequins ctDNA Evaluation Set
Maximize insights from every sample with Sequins™ internal standards

Customizable Control Backbone with Molecular Ladder
The Sequins ctDNA Evaluation Set targets nine clinically important cancer gene variants at precise variant allele frequencies and is applicable to a range of cancers. Sequins are pre-mixed in a single tube and can be spiked-in to each sample prior to library preparation and sequencing.
Gene | Cosmic UID | Variant | VAF % |
---|---|---|---|
BRAF | COSV56056643 | c.1799T>A (Substitution) | p.V600E Missense | 5% |
ESR1 | COSV52781024 | c.1613A>G (Substitution) | p.D538G Missense | 5% |
PTEN | COSV64288845 | c.968dup (Insertion) | p.N323Kfs*2 Insertion/frameshift | 5% |
NRAS | COSV54736340 | c.182A>G (Substitution) | p.Q61R Missense | 1% |
EGFR | COSM26352 | c.? | p.V769_D770insASV (Insertion – In frame) | 1% |
KRAS | COSV55497369 | c.35G>A (Substitution) | p.G12D Missense | 1% |
TP53 | COSV52661282 | c.659A>G (Substitution – Missense) | 0,1% |
BRCA1 | COSV58786277 | c.68_69del (Deletion) | pE23Vfs*17 (Frameshift) | 0,1% |
BRCA2 | COSV66447676 | c.5946del | p.S1982Rfs*22 (deletion – frameshift) | 0,1% |
The Sequins ctDNA Evaluation Set can be used as a backbone for further customization with additional gene targets through our Sequins On-Demand program.
